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An epidemic of dengue hemorrhagic fever and dengue shock syndrome in children in Delhi.
Indian Pediatr ; 1998 Aug; 35(8): 727-32
Artículo en Inglés | IMSEAR | ID: sea-11098
ABSTRACT

OBJECTIVE:

To study clinical profiles and outcome of children of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) during 1996 Delhi epidemic.

DESIGN:

Retrospective study.

SETTING:

Hospital based study.

METHODS:

Children hospitalized from September to November 1996 were studied. All patients were diagnosed, managed and monitored according to a standard protocol.

RESULTS:

One hundred and thirty four children (80 (60%) males and 54 (40%) females) were studied. Sixty (45%) children were less than 6 years of age of which 12 presented during infancy. There were 92 (67%) cases of DHF and 42 (33%) cases of DSS. Common symptoms were fever (93%), abdominal pain (49%) and vomiting (68%). The commonest hemorrhagic manifestation was hematemesis (39%) followed by epistaxis (36%) and skin bleeds (33%). Hepatomegaly was observed in 97 (72%) cases and splenomegaly in 25 (19%). Serology was positive (IgM hemaglutination antibody titres > 1 160) for dengue type 2 in 31 (80%) of 39 patients in whom sera was tested during the acute phase of illness. Mortality was 6%. Hematocrit > 40% was observed in only 25 (18%) patients and hence the management protocol was based on clinical signs and symptoms and not on hematocrit.

CONCLUSIONS:

A management protocol of DHF/DSS in which fluid therapy is not based on haematocrit values needs to be formulated.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Esplenomegalia / Vómitos / Femenino / Humanos / Masculino / Inmunoglobulina M / Dolor Abdominal / Niño / Preescolar / Epistaxis Tipo de estudio: Guía de Práctica Clínica / Estudio observacional País/Región como asunto: Asia Idioma: Inglés Revista: Indian Pediatr Año: 1998 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Esplenomegalia / Vómitos / Femenino / Humanos / Masculino / Inmunoglobulina M / Dolor Abdominal / Niño / Preescolar / Epistaxis Tipo de estudio: Guía de Práctica Clínica / Estudio observacional País/Región como asunto: Asia Idioma: Inglés Revista: Indian Pediatr Año: 1998 Tipo del documento: Artículo