Schistosoma haematobium and urinary tract pathogens co-infections in a rural community of Edo State, Nigeria.

ABSTRACT

A survey of S. haematobium and other urinary tract pathogens co-infection was carried out among 198 volunteers in Ihieve, Ogben, a rural community in Owan East Local Government Area of Edo State, Nigeria. Of these, 118 (59.5%) had S. haematobium ova in their urine samples. Light infection (< or =50 ova/l0 ml) occurred among 49 (24.7%) volunteers and 59 (29.8%) inhabitants had heavy infections (> 50 ova/10 ml). The children 68 (64.2%) were more infected their the adults 50 (54.3%). This difference was statistically significant at (chi2 = 60.37, P < 0.05). The prevalence of S. haematobium among the males 80 (71.4%) was higher than their female counterparts 38 (41.9%) and this difference is statistically significant at (t = 1.28) Bacteriuria and bacterial isolates occurred among 60 (30.3%) with S haematobium infection. Three nitrate reducing bacterial isolates namely; Klebsiella sp and Staphylococcus aureus, Escherichia coli and a fungus; Candida albicans were reported in their urine cultures. Multiple infections were observed among 43 S. haematobium infected persons. The antibiogram of the isolates indicated that Nitrofurantoin, Gentamycin and otramax were the most effective drugs for the management of bacterial infections among these volunteers. All the bacterial isolates were resistant to Cloxacillin and Augmentum. The C. albicans were sensitive to Diflucan, Nizoral, Gynotravogen, Gynotrosydovule, Gyno-daktarin and Mycostatin.