Glutathione and associated enzymes in toxic cataractogenesis-selenite model.
J Environ Biol
;
2006 Oct; 27(4): 733-8
Artículo
en Inglés
| IMSEAR
| ID: sea-113311
ABSTRACT
Glutathione, gamma-glutamyl cysteine synthetase (gamma -GCS) and glutathione reductase (GSH-R) activity were determined biochemically in the lens during various stages after subcutaneous administration of sodium selenite in multiple low dosages and single high dosages. The GSH concentration and gamma-GCS and GSH-R activity declined progressively after the selenite administration. The changes observed were discussed in relation to the possible role of selenite interaction with GSH and the enzymes.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Catarata
/
Femenino
/
Masculino
/
Ratas Wistar
/
Selenito de Sodio
/
Modelos Animales de Enfermedad
/
Relación Dosis-Respuesta a Droga
/
Glutamato-Cisteína Ligasa
/
Glutatión
Idioma:
Inglés
Revista:
J Environ Biol
Año:
2006
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS