Protective role of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in human lymphocytes in vitro.
J Environ Biol
;
2007 Apr; 28(2): 279-82
Artículo
en Inglés
| IMSEAR
| ID: sea-113879
ABSTRACT
Antioxidants and plant products are reported to reduce the genotoxic damage of steroids. In our present study we have tested different dosages of nordihydroguaiaretic acid (NDGA) against the genotoxic damage induced by ethynodiol diacetate in the presence of S9 mix. Treatments with nordihydroguaiaretic acid (NDGA) results in the reduction of the genotoxic damage. A significant decrease was observed at all the tested doses of NDGA in sister chromatic exchanges of number of abnormal cells. The results suggest a protective role of NDGA against the genotoxic damage.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Intercambio de Cromátides Hermanas
/
Daño del ADN
/
Masoprocol
/
Femenino
/
Humanos
/
Linfocitos
/
Células Cultivadas
/
Aberraciones Cromosómicas
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Anticonceptivos Sintéticos Orales
/
Sustancias Protectoras
Idioma:
Inglés
Revista:
J Environ Biol
Año:
2007
Tipo del documento:
Artículo
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