Efficacy of 5-fluorouracil in combination with methoxyphenyl maleamic acid in murine tumors.
J Postgrad Med
;
1991 Oct; 37(4): 211-5
Artículo
en Inglés
| IMSEAR
| ID: sea-115144
ABSTRACT
Combination chemotherapy studies were carried out in vivo against sarcoma 180 (ascites)(S180) and Ehrlich (ascites) carcinoma (EAC) tumours using cytotoxic drugs and methoxyphenyl maleamic acid (MPMA), an intermediate in the synthesis of pyrrolidine-nitrogen-mustards. Preliminary data have suggested that the combination of 5-fluorouracil (5-FU) and methoxyphenyl maleamic acid (MPMA) was more active than 5-FU used singly against EAC tumour. The possible therapeutic potential of this combination was further investigated in EAC tumour.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Sarcoma 180
/
Femenino
/
Masculino
/
Carcinoma de Ehrlich
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Distribución Aleatoria
/
Quimioterapia Combinada
/
Fluorouracilo
/
Animales
/
Maleatos
Idioma:
Inglés
Revista:
J Postgrad Med
Año:
1991
Tipo del documento:
Artículo
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