Oral cancer among patients under the age of 35 years.
J Postgrad Med
;
2001 Jul-Sep; 47(3): 171-6
Artículo
en Inglés
| IMSEAR
| ID: sea-116345
ABSTRACT
BACKGROUND:
Cancer of the oral cavity is one of the commonest cancers among males.AIMS:
To assess the aetiological factors, patient characteristics, treatment and the outcome in young patients with oral cancer. SETTINGS ANDDESIGN:
A retrospective descriptive study of patients under the age of 35 years with cancer of the oral cavity treated between 1982-1996, with the last follow-up till 2001, using the tumour registry data of Regional Cancer Centre (RCC), Trivandrum, Kerala, India. SUBJECT ANDMETHOD:
The detailed clinical, treatment and follow-up data were obtained from the computerised records of RCC and recorded on a preset proforma. This was analysed with emphasis on age, sex, risk factors, site, histology, clinical extent and treatment methods and survival in the study group. STATISTICALANALYSIS:
The survival analysis was carried by Kaplan-Meier method and the difference in survival was analysed using log-rank test.RESULTS:
Out of 264 patients analysed, tongue was the commonest site identified in 136 (52%) patients followed by buccal mucosa in 69 (26%) patients. A male female ratio of 2.31 was observed with a significantly higher male preponderance in buccal mucosa (4.31). Prior exposure to tobacco or alcohol was noted in 59.4% patients, with more habitués in buccal mucosa cancer. Histological confirmation was present only in 83.7% patients and among them most were squamous cell carcinoma (85.9%). Radiotherapy, surgery or combined modalities of treatment were employed for majority of patients. The 5-year survival was 57.3%. T stage of the tumour was found to be significant in predicting disease free survival (P=0.03).CONCLUSIONS:
The importance of early detection for clinical down staging is stressed. There is a need to investigate the aetiology of intra oral cancers in younger patients since a significant proportion (almost 40%) of these patients do not have associated risk factors for cancer.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Factores de Tiempo
/
Femenino
/
Humanos
/
Masculino
/
Neoplasias de la Boca
/
Carcinoma de Células Escamosas
/
Análisis de Supervivencia
/
Estudios Retrospectivos
/
Factores de Riesgo
/
Estudios de Seguimiento
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
/
Estudio de tamizaje
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
J Postgrad Med
Año:
2001
Tipo del documento:
Artículo
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