Singular anti-RNA virus-directed proteins.
J Postgrad Med
;
2000 Jul-Sep; 46(3): 164-71
Artículo
en Inglés
| IMSEAR
| ID: sea-116522
ABSTRACT
AIMS:
To additionally purify and characterise the anti-RNA virus-directed protein termed p14. MATERIALS ANDMETHODS:
Antiviral assays of p14 against RNA and DNA viruses were carried out and its antigenic similarities with chicken interferon (CIFN) were studied. HPLC-Reverse Phase of p14 was performed to further purify p14.RESULTS:
p14 showed antiviral activity against RNA viruses only and not against DNA viruses. It was antigenically distinct from CIFN. Purification of p14 yielded three proteins with antiviral activity, which had different physico-chemical properties than those described for interferons.CONCLUSIONS:
The data presented on the antiviral, immunological and physico-chemical properties, establish the unique nature of p14 vis-á-vis those of interferons.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Virus ARN
/
Proteínas del Helminto
/
Células Cultivadas
/
Embrión de Pollo
/
Cromatografía Líquida de Alta Presión
/
Sensibilidad y Especificidad
/
Virus ADN
/
Animales
/
Proteínas Musculares
Tipo de estudio:
Estudio diagnóstico
Idioma:
Inglés
Revista:
J Postgrad Med
Año:
2000
Tipo del documento:
Artículo
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