Concerns on the dosing of antitubercular drugs for children in RNTCP.
Indian Pediatr
;
2008 Oct; 45(10): 852-4
Artículo
en Inglés
| IMSEAR
| ID: sea-11795
ABSTRACT
The Revised National Tuberculosis Control Program (RNTCP) has initiated provision of antitubercular therapy for children with strategy of patient-wise boxes for the 4 different weight bands (6- 10 kg; 11- 17 kg; 18- 25 kg; 26- 30 kg). We evaluated the dose of individual drugs delivered by this approach to children of varying weights. The following areas of concern were identified underdosing of individual antitubercular drugs for many weights; lack of provision to modify doses when child gains weight and moves to another weight band; and, inappropriate formulations, particularly for infants. We conclude that the current dosing strategy used in RNTCP needs modification to prevent the significant risk of underdosing and undertreatment.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Tuberculosis
/
Peso Corporal
/
Humanos
/
Control de Enfermedades Transmisibles
/
Protocolos Clínicos
/
India
/
Programas Nacionales de Salud
/
Antituberculosos
Tipo de estudio:
Guía de Práctica Clínica
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian Pediatr
Año:
2008
Tipo del documento:
Artículo
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