Systemic lupus erythematosus in Indian children.
Indian Pediatr
;
1989 Sep; 26(9): 868-73
Artículo
en Inglés
| IMSEAR
| ID: sea-12289
ABSTRACT
Twenty cases of systemic lupus erythematosus (SLE) in prepubertal children (less than 14 years of age) were seen over a period of 14 years. The malefemale ratio was 12.3, and the mean age at onset was 9.37 years. Fever with joint involvement was the commonest presenting manifestation (60%), followed by nephrotic syndrome (25%). Notable clinical features included a high incidence of renal involvement (75%), significant hypertension (45%) and reversibility of acute renal failure (2 cases). The other organs and systems involved included mucocutaneous manifestations (60%), cardiovascular system (30%), respiratory system (25%), neuropsychiatric manifestations (45%), and anemia (75%). Raynaud's phenomenon and thrombocytopenia were rare while leucopenia was not seen in a single patient. Immunological abnormalities noted were 100% positivity for antinuclear antibodies, and 87.5 and 75% positivity for antibodies to double-stranded and single-stranded DNA, respectively. Hypocomplementemia was seen in 75% of patients tested.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Lupus Eritematoso Cutáneo
/
Nefritis Lúpica
/
Femenino
/
Humanos
/
Masculino
/
ADN
/
Niño
/
Preescolar
/
Anticuerpos Antinucleares
/
Adolescente
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian Pediatr
Año:
1989
Tipo del documento:
Artículo
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