Clinical trial of indigenous antipyretic: Testing of antipyretic efficacy of five triditional medicine formulation on TAB-induce pyrexial volunteers
Artículo
| IMSEAR
| ID: sea-125331
ABSTRACT
Two grams each of five traditional medicine formulations (TMF), TMF-06, TMF-24, TMF-25, TMF-35A and TMF-35B- orally administered with 150 ml of betel leaf preparation, had underwent a clinical trial of antipyretic efficacy on a total of 315 TAB-induced pyrexial Burmese volunteers. Both positive control of acetyl sallicylate 600 mg orally and negative control of no drug treatment were included. The trial design was performed on a single (observer) blind basis. Effectiveness of the agents at the peak of induced pyrexia were observed for three hours. Only TMF-06 possessed the antipyretic efficacy (78-88 per cent) as could be observed in 87-96 per cent of responders, in comparison to those of the acetyl salicylate. Nevertheless, TMF-24 and TMF-35B showed a lesser antipyretic activity. Therefore, TMF-06 was found to be the most recommendable antipyretics to be used at indigenous medicine centres.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Antiinflamatorios no Esteroideos
/
Ensayos Clínicos como Asunto
/
Mianmar
/
Evaluación de Medicamentos
Tipo de estudio:
Ensayo Clínico Controlado
País/Región como asunto:
Asia
Año:
1989
Tipo del documento:
Artículo
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