Role of cimetidine in prevention and treatment of stress induced gastric bleeding in neonates.
Indian Pediatr
;
1990 May; 27(5): 465-9
Artículo
en Inglés
| IMSEAR
| ID: sea-12609
ABSTRACT
Gastric bleeding from stress ulcers in acutely sick infants frequently signals impending mortality. This study was carried out to evaluate the efficacy of cimetidine in preventing and treating stress ulcers in such neonates. One hundred babies were included in this study. Out of this, 32 babies were given prophylactic cimetidine and 68 neonates acted as controls. It was observed that the babies on prophylactic cimetidine fared better than controls. In the second part of study, 77 neonates with clinical evidence of hemorrhage were included, 43 were put on cimetidine and 34 acted as controls. It was observed that babies on cimetidine therapy showed a better response. The gastric bleeding stopped earlier, and more babies responded favourably to this therapy. Use of cimetidine in stress induced bleeding in high risk neonates is recommended.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Úlcera Gástrica
/
Estrés Fisiológico
/
Humanos
/
Recién Nacido
/
Cimetidina
/
Evaluación de Medicamentos
/
Hemorragia Gastrointestinal
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Inglés
Revista:
Indian Pediatr
Año:
1990
Tipo del documento:
Artículo
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