A paired comparison study of ThinPrep Pap test and conventional cervical pap smears in Srinagarind Hospital, a preliminary report

ABSTRACT

Objective: To compare the cytologic diagnosis of a liquid-base, Thin-layer preparation and conventional cervical smear.Material and Method: Ninety nine cervical smears were processed conventional method and with the ThinPrepÒ Pap test. Cytologic diagnosis based on the Bethesda system 2001.Results: Of the 99 pair slides of conventional and ThinPrep Pap test smears interpreted during the study period. All smears were cytologic diagnosed as negative for intraepithelial lesion or malignancy (90 conventional and 85 ThinPrep smears), atypical squamous cells of undertermined significance, ASC-US (1 conventional and 5 ThinPrep smears), low-grade squamous intraepithelial lesion, LSIL (0 conventional and 2 ThinPrep smears), high-grade squamous intraepithelial lesion, HSIL (4 conventional and 3 ThinPrep smears), Invasive cervical cancer (4 agreement by conventional and ThinPrep smears).Conclusion: The ThinPrep Pap test is more sensitive method of detecting ASC-US and squamous intraepithelial lesion than the conventional Pap smear in this preliminary study.