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Intravitreal bevacizumab for choroidal neovascular membrane associated with Best's vitelliform dystrophy.
Indian J Ophthalmol ; 2010 Mar; 58(2): 160-162
Artículo en Inglés | IMSEAR | ID: sea-136048
ABSTRACT
Best's vitelliform macular dystrophy is a hereditary form of progressive macular dystrophy that can be complicated by choroidal neovascularization. Authors report successful treatment of choroidal neovascularization with intravitreal bevacizumab in one such eye in an ‘adult’ Indian male with visual improvement. A 23-year-old male presented with diminution of vision in the right eye for the past sixteen months. Visual acuity was 20/400 in the that eye. After three consecutive intravitreal injections of bevacizumab (1.25 mg/0.05 ml), vision improved to 20/120. Seven months following the last injection of bevacizumab, fundus appeared stable and visual acuity was maintained. No drug-related ocular or systemic side effects were encountered. To the best of our knowledge (PubMed search), this is the first report of its kind in an adult Indian patient. Intravitreal bevacizumab appears to be a promising and cost-effective modality of treatment in such eyes with potential for improvement in vision. However, a long-term follow-up is warranted.
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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Humanos / Masculino / Agudeza Visual / Neovascularización Coroidal / Inhibidores de la Angiogénesis / Adulto Joven / Inyecciones Intraoculares / Anticuerpos Monoclonales Humanizados / Degeneración Macular / Anticuerpos Monoclonales Idioma: Inglés Revista: Indian J Ophthalmol Año: 2010 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Humanos / Masculino / Agudeza Visual / Neovascularización Coroidal / Inhibidores de la Angiogénesis / Adulto Joven / Inyecciones Intraoculares / Anticuerpos Monoclonales Humanizados / Degeneración Macular / Anticuerpos Monoclonales Idioma: Inglés Revista: Indian J Ophthalmol Año: 2010 Tipo del documento: Artículo