The occurrence of granulation tissue at Vaginal vault from different suture materials of vault closure following hysterectomy.

ABSTRACT

A randomized double blind clinical trial was carried out in order to compare the occurrence of vaginal vault granulations between vaginal closure, using interrupted figure-of-eight sutures with chromic catgut and poliglecaprone 25 (MonocrylR). One hundred and twelve healthy patients who underwent total abdominal hysterectomy were randomly assigned to one of the two studied suture materials. Six weeks after the operation, the patients were examined blindedly whether there were vaginal vault granulations. The characteristics of both studied groups were comparable. The incidence of vaginal vault granulations in patients was 33.9%. The granulations occurred in 19.6% in the poliglecaprone 2. And 48.2% in the chromic catgut suture material group (P<0.01). In patients with vaginal vault granulation, 76.3% had abnormal vaginal discharge and/or bleeding, while only 6.7% of those without had (P<0.01). Closure of vaginal vault with poliglecaprine 25 should be employed in case of total abdominal hysterectomy because of decreasing the occurrence of vaginal vault granulations later on.