Serum gamma-glutamyl transpeptidase and alkaline phosphatase activities in normal and hepatic disorders.

ABSTRACT

Serum gamma-glutamyl transpeptidase (gamma-glutamyl transferase EC 2.3.2.2) and alkaline phosphatase (EC 3.1.3.1) activities from 115 adults with various hepatic diseases were compared to 200 normal adults. Although the values of both enzymes are significantly above normal in the same liver disorders, the first enzyme is much more sensitive in liver cirrhosis. The two enzymes are correlated very well (r = 0.648, p < 0.0005) in hepatic patients.