High risk of essential hypertension in males with intron 4 VNTR polymorphism of eNOS gene.
Indian J Hum Genet
;
2009 May; 15(2): 49-53
Artículo
en Inglés
| IMSEAR
| ID: sea-138870
ABSTRACT
In this study 250 patients with essential hypertension were investigated in comparison to 218 normotensives for association with epidemiological parameters. Of these DNA samples from 176 patients and 168 controls were analyzed for intron 4 27bp repeat polymorphism of eNOS gene. The study revealed significantly high risk of essential hypertension for individuals who were obese, with a positive family history and with non-vegetarian food habits. Though the intron 4b/a polymorphism of eNOS gene did not reveal any association with essential hypertension in general, males with a/a genotype of the polymorphism did show significantly high risk for developing hypertension.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Femenino
/
Humanos
/
Masculino
/
Intrones
/
Familia
/
Riesgo
/
Predisposición Genética a la Enfermedad
/
Óxido Nítrico Sintasa de Tipo III
/
Preferencias Alimentarias
/
Genotipo
Tipo de estudio:
Estudio de etiología
/
Factores de riesgo
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian J Hum Genet
Año:
2009
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS