Association between gingival crevicular fluid prostaglandin E 2 level and preterm low birth weight.
Artículo
en Inglés
| IMSEAR
| ID: sea-140195
ABSTRACT
Background:
Periodontal infections, which serve as a reservoir of inflammatory mediators such prostaglandin E 2 (PGE 2 ), may pose a threat to the fetal-placental unit and cause preterm delivery.Aim:
This study was conducted to estimate the PGE 2 levels in gingival crevicular fluid (GCF) and to explore the association between GCF-PGE 2 levels and preterm low birth weight (PLBW). Materials andMethods:
Twenty-two pregnant patients were selected for the study. GCF samples were collected from these patients before delivery and again at 1 month after delivery. PGE 2 level was estimated using a commercially available ELISA kit (Neogen™).Results:
The mean GCF-PGE 2 level was 5.8 ng/ml before parturition and 5.5 ng/ml after parturition, but the difference was not statistically significant. There was negative correlation between PGE 2 levels and gestational age at birth.Conclusion:
The study provides weak evidence that there is correlation between GCF-PGE 2 levels and birth outcome. Further clinical trials with large samples are required to confirm the association between GCF-PGE 2 levels and PLBW.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Peso al Nacer
/
Femenino
/
Humanos
/
Recién Nacido de Bajo Peso
/
Recién Nacido
/
Embarazo
/
Resultado del Embarazo
/
Dinoprostona
/
Índice de Higiene Oral
/
Índice Periodontal
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Idioma:
Inglés
Año:
2012
Tipo del documento:
Artículo
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