JAK2-positive Philadelphia-negative myeloproliferative neoplasms.
Indian J Pathol Microbiol
;
2011 Jan-Mar 54(1): 117-120
Artículo
en Inglés
| IMSEAR
| ID: sea-141929
ABSTRACT
The recent discovery of the JAK2 mutations has rekindled interest in the approach to classic BCR/ABL-negative myeloproliferative neoplasms (MPNs) in terms of both diagnostic evaluation and treatment. However, additional clinical, laboratory and histological parameters play a key role to allow diagnosis and subclassification, regardless of whether JAK2 V617F mutation is present or not. Here are two cases which incidentally presented with splenomegaly and moderate leukocytosis, and were diagnosed as MPN-primary myelofibrosis (PMF) in prefibrotic phase and polycythemia vera (PV), respectively, using revised World Health Organization (WHO) 2008 criteria.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Policitemia Vera
/
Esplenomegalia
/
Organización Mundial de la Salud
/
Biopsia
/
Femenino
/
Humanos
/
Masculino
/
Neoplasias de la Médula Ósea
/
Janus Quinasa 2
/
Mielofibrosis Primaria
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
2011
Tipo del documento:
Artículo
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