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Protein C and protein S: Causative factor for developing a hemorrhagic infarct in a HbE/Beta thalassemia child.
Indian J Pediatr ; 2010 Mar; 77(3): 316-317
Artículo en Inglés | IMSEAR | ID: sea-142529
ABSTRACT
A 10-yr-old HbE/Beta thalassemia child who developed subacute to chronic occipitotemporal hemorrhagic infarct with smaller chronic infarct with gliotic changes in the left frontal periventricular white matter. Genetic tests showed that patient was positive for HbE and IVS1-5 mutation and was negative for thrombogenic mutations. Hemorrhagic infarct was confirmed by magnetic resonance imaging study. Antigenic levels of Protein C and Protein S were low. Based on these outcomes, it was concluded that Protein C and Protein S deficiency were the causative factor for developing hemorrhagic infarct in the HbE/ Beta thalassemia patient.
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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Humanos / Masculino / Imagen por Resonancia Magnética / Hemorragia Cerebral / Infarto Cerebral / Niño / Talasemia beta / Deficiencia de Proteína S / Deficiencia de Proteína C Idioma: Inglés Revista: Indian J Pediatr Año: 2010 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Humanos / Masculino / Imagen por Resonancia Magnética / Hemorragia Cerebral / Infarto Cerebral / Niño / Talasemia beta / Deficiencia de Proteína S / Deficiencia de Proteína C Idioma: Inglés Revista: Indian J Pediatr Año: 2010 Tipo del documento: Artículo