Apolipoprotein E isotype distribution amongst Ramgharias of Punjab.
Indian J Hum Genet
;
2000 Jan; 6(1): 1-5
Artículo
en Inglés
| IMSEAR
| ID: sea-143497
ABSTRACT
Apolipoprotein E is a major constituent of chylomicrons and HDL fractions of the normal blood plasma involved in lipid transfer systems. The three common alleles apoE2, apoE3 and apoE4 with six possible phenotypes have been identified at this locus in all the populations of the world studied so far, with apoE3 being the most common. The present study employed PCR restriction isotyping techniques to estimate allele frequency distribution amongst Ramgharias an artisan caste group of Punjab in North India. The methodology was developed to visualise the isotypes on PAGE using silver staining. The major genotypes observed were E2/3, E3/3 and E3/4 with allele frequencies APO E2=0.107, APOE3=0.714 AND APO E4=0.179.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Idioma:
Inglés
Revista:
Indian J Hum Genet
Año:
2000
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS