Pancreatic carcinogenesis: The impact of chronic pancreatitis and its clinical relevance.
Indian J Cancer
;
2009 Oct-Dec; 46(4): 288-296
Artículo
en Inglés
| IMSEAR
| ID: sea-144264
ABSTRACT
Pancreatic cancer is a devastating disease with a dismal prognosis and early detection remains a challenge. On the background that inflammation is one of the key steps in the development of cancer, it is natural that chronic pancreatitis is considered as one of the etiological factors for the development of pancreatic cancer. However, the process of pancreatic carcinogenesis is a multifactorial phenomenon rather than a process that evolves solely via inflammation. This review attempts to put into perspective the association between different etiological forms of chronic pancreatitis and pancreatic cancer, and the diverse mechanisms operational in the process of pancreatic carcinogenesis. Furthermore, the clinical relevance of the current understanding of the relationship between chronic pancreatitis and pancreatic cancer, especially with regard to the pancreatic head mass of uncertain etiology, is discussed in this review.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Neoplasias Pancreáticas
/
Humanos
/
Transformación Celular Neoplásica
/
Factores de Riesgo
/
Pancreatitis Crónica
/
Inflamación
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
/
Factores de riesgo
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
Indian J Cancer
Año:
2009
Tipo del documento:
Artículo
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