Studies on effects of chronic exposure of endosulfan to Labeo rohita.

ABSTRACT

The major carp, Labeo rohita (Hamilton) upon chronic exposure to endosulfan showed hyperglycemia (60.11 to 117.71 mg 100 ml-1) and hypercholestemia (51.78 to 76.87 mg 100 ml-1) of blood when compared to the control. As a result of the insecticidal stress, the tissue metabolites and enzymes like AST and ALT revealed significant alterations. The hormones T3 (0.53 to 1.35 /ml l-1) and TSH (0.48 to 0.32 /ml l-1) were also affected by the endosulfan even in sub lethal concentration. Signficant histopathological alterations were observed in liver and gill of treated fishes. The reason for the significant alterations in tissue sugars, aminoacids, cholesterol, protein, enzymes and homones and the histopathological changes is discussed.