Histiocytosis Syndromes of Childhood: A report of four cases.
Artículo
en Inglés
| IMSEAR
| ID: sea-147090
ABSTRACT
Histiocytosis Syndromes of Childhood (HSC) are a group of rare and diverse disorders characterized by aggressive proliferation or accumulation of cells of monocyte - macrophage system of bone marrow. The clinical spectrum of this syndrome is distinctly varied. The exact pathophysiology of HSC is yet to be determined; however, evidence suggests that one of the subtypes, Hemophagocytic Lymphohistiocytosis, is due to decreased Natural Killer cell activity, resulting in increased activation of other T cell subtypes and production of cytokines. We present four cases of HSC managed at our center between October 2008 & February 2010.
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Índice:
IMSEAR (Asia Sudoriental)
Idioma:
Inglés
Año:
2010
Tipo del documento:
Artículo
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