Efficacy of antibacterial activity of garlic cloves from Tamil Nadu and Jowai region.

ABSTRACT

Background: The development of antibiotic resistance has become a global health challenge which is causing ineffectiveness of the available antibacterial agents leading to increase in diseases and death rate. Therefore this study intends to investigate the antibacterial action of Aqueous Garlic Extract (AGE) against 9 multidrug-resistant gram-positive and gram-negative bacterial isolates, including Staphylococcus aureus, Enterococcus species, ß hemolytic streptococcus, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, Escherichia coli, Vibrio cholerae and Serretia marscenes. Methods: Antibacterial activity of different concentrations of AGE by well-diffusion method was recorded by measuring the diameter of zone of inhibition. The Tamil Nadu garlic cloves as well as Jowai region garlic cloves showed antibacterial activity against both GPC and GNR. Results: The maximum zone of inhibition was observed in Tamil Nadu garlic than that of Jowai region, but the only bacteria which showed a better zone of inhibition with Jowai region than Tamil Nadu garlic was Pseudomonas aeruginosa. Conclusion: Thus our study reveals that garlic not only makes the food more spicy & edible with its flavour but can also be used as an effective antibacterial agents against MDR gram positive & gram negative bacteria.