Use of rituximab in pemphigus patients with chronic viral hepatitis: Report of three cases.
Indian J Dermatol Venereol Leprol
;
2014 Spt-Oct ; 80 (5): 422-426
Artículo
en Inglés
| IMSEAR
| ID: sea-154925
ABSTRACT
Use of rituximab in patients with chronic viral hepatitis can worsen pre-existing hepatitis or reactivate occult infection. There are no reports of use of rituximab in pemphigus patients with co-existing viral hepatitis. Herein, we report three pemphigus patients with co-existing chronic viral hepatitis (hepatitis C (n = 2), hepatitis B (n = 1)), who were treated successfully with rituximab under close supervision and concurrent antiviral drug administration. There was no derangement of the liver function tests or increase in viral load in any of the patients. By incorporating good collaboration with a hepatologist and close follow-up, such patients can be managed successfully with biologic therapies when the conventional treatment modalities have failed.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Antivirales
/
Femenino
/
Humanos
/
Masculino
/
Pénfigo
/
Adulto
/
Hepatitis B Crónica
/
Hepatitis C Crónica
/
Fármacos Dermatológicos
/
Anticuerpos Monoclonales de Origen Murino
Idioma:
Inglés
Revista:
Indian J Dermatol Venereol Leprol
Año:
2014
Tipo del documento:
Artículo
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