Drug Eruptions Induced by Allopurinol Associated with HLA-B*5801.
Indian J Dermatol Venereol Leprol
;
2015 Jan-Feb; 81(1): 43-45
Artículo
en Inglés
| IMSEAR
| ID: sea-154971
ABSTRACT
Allopurinol, a drug commonly used for treating gout and hyperuricemia, is a frequent cause of drug eruptions. Recent investigations suggest that HLA‑B*5801 allele is a very strong marker for allopurinol‑induced cutaneous adverse drug reactions (cADRs). In this article we report two cases of allopurinol‑induced drug eruptions in patients carrying the HLA‑B*5801 allele and review the literature on the association between HLA‑B*5801 and allopurinol‑induced cADRs based on a MEDLINE and PubMed search.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Anciano
/
Masculino
/
Antígenos HLA-B
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Alopurinol
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MEDLINE
/
Erupciones por Medicamentos
/
PubMed
/
Persona de Mediana Edad
Idioma:
Inglés
Revista:
Indian J Dermatol Venereol Leprol
Año:
2015
Tipo del documento:
Artículo
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