Factors predicting recurrence in successfully treated cases of anisometropic amblyopia.
Indian J Ophthalmol
;
2013 Nov ; 61 (11): 630-633
Artículo
en Inglés
| IMSEAR
| ID: sea-155443
ABSTRACT
Context Recurrence after successful treatment of amblyopia is known and understanding the risk factors could help effective management. Aim:
To measure incidence of recurrence in successfully treated cases of anisometropic amblyopia and evaluate factors predicting it. Settings andDesign:
Cohort Study at a tertiary level institution. Materials andMethods:
Successfully treated anisometropic amblyopes aged 4−12 years were followed up for 1 year after stopping therapy. Best corrected visual acuity (BCVA), refractive error, stereoacuity and contrast sensitivity were evaluated at baseline and follow‑up. StatisticalAnalysis:
Intergroup analysis with appropriate tests Chi‑square test, Fisher’s exact test, Wilcoxon rank sum test and paired t‑test.Results:
One hundred and two patients with mean age at diagnosis 7.06 ± 1.81 years were followed‑up for a mean duration of 1.0 ± 0.2 years. The mean pre‑treatment BCVA (LogMAR score) at diagnosis was 0.73 ± 0.36 units which improved to 0.20 ± 0.00 with treatment and after 1 year of stopping treatment was 0.22 ± 0.07. Thirteen (12.74%) patients showed amblyopia recurrence during follow‑up. Risk of recurrence was higher with older age of onset of treatment (6.64 ± 1.77 years without recurrence v/s 8.53 ± 1.39 years with recurrence, P = 0.0014). Greater extent of improvement of VA (P = 0.048) and final VA at stopping occlusion (P = 0.03) were associated with higher recurrence. Binocularity status or stereoacuity changes were not associated with risk of recurrence.Conclusions:
Significant numbers of children suffer recurrence of amblyopia after stopping therapy. Older age, better BCVA after stopping therapy and greater magnitude of improvement in BCVA are important risk factors for recurrence. Careful follow‑up is essential for early detection and management of recurrence.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
Indian J Ophthalmol
Año:
2013
Tipo del documento:
Artículo
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