Carnitine supplementation in diphtheria.
Indian Pediatr
;
1992 Dec; 29(12): 1501-5
Artículo
en Inglés
| IMSEAR
| ID: sea-15574
ABSTRACT
We studied the effect of carnitine supplementation in patients with diphtheria. Six hundred and twenty five children of diphtheria received either DL-carnitine (100 mg/kg/day in two divided doses orally for four days), or no carnitine, in addition to the routine treatment for diphtheria. The patients receiving carnitine (n = 327) and controls (n = 298) were matched for age, sex, duration of symptoms, grade of toxemia and immunization status. Patients receiving carnitine showed a significant reduction in incidence of myocarditis as compared to controls (p = 0.001). Cases with myocarditis receiving carnitine therapy showed a significant reduction in mortality as compared to controls (p < 0.001). In view of a significant decline in incidence and mortality of myocarditis in cases of diphtheria, we recommended that all cases with diphtheria should receive carnitine supplementation.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Brasil
/
Femenino
/
Humanos
/
Masculino
/
Carnitina
/
Niño
/
Preescolar
/
Incidencia
/
Difteria
/
Lactante
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio de incidencia
/
Estudio pronóstico
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Indian Pediatr
Año:
1992
Tipo del documento:
Artículo
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