Comparison of amine fluoride and chlorhexidine mouth rinses in the control of plaque and gingivitis – A randomized controlled clinical trial.

Objectives: The objective of this triple blind randomized controlled clinical trial was to compare the efficacy of a mouth rinse containing amine fluoride (AmF) and chlorhexidine in controlling the supragingival plaque accumulation and gingival inflammation during a 4‑week period in patients with chronic gingivitis. Subjects and Methods: A total of 30 patients were participated in this study. Fifteen patients were prescribed an AmF‑containing mouth rinse and 15 were prescribed a chlorhexidine mouth rinse. Plaque index, gingival index, bleeding index, tooth stain, and tongue stain (TS) were recorded at baseline, 15 days and 1‑month. Patients’ perception of odor, taste and any discomfort were recorded. Results: The comparisons between the groups were done using Mann–Whitney U‑test. The comparison within the group at different time visits were done using Wilcoxon signed rank test. Both the mouth rinses resulted in a significant decrease in plaque index, gingival index, bleeding index. However, AmF mouth rinse resulted in a statistically significant decrease in bleeding index and gingival index compared to chlorhexidine group. There was no significant difference in tooth stain and TS in both the groups. Conclusions: The 4 weeks use of AmF containing mouth rinse is effective in reducing the gingival inflammation and plaque.