Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation.
Indian J Exp Biol
;
2015 Apr; 53(4): 228-231
Artículo
en Inglés
| IMSEAR
| ID: sea-158428
ABSTRACT
Sclerotiorin, isolated from the fermented broth of Penicillium frequentans, exhibited potent inhibition against human polymorphonuclear leukocytes 5-lipoxygenase and human platelet aggregation with a half maximal value 36 µM and 250 µM, respectively. Further, the Ames test has demonstrated the sclerotiorin to be non-mutagenic.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Penicillium
/
Salmonella typhimurium
/
Benzopiranos
/
Araquidonato 5-Lipooxigenasa
/
Inhibidores de Agregación Plaquetaria
/
Pruebas de Mutagenicidad
/
Neutrófilos
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2015
Tipo del documento:
Artículo
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