Dipyrone-induced changes in DNA repair and other cell membrane associated processes in Escherichia coli.
J Biosci
;
1982 Sept; 4(3): 317-326
Artículo
en Inglés
| IMSEAR
| ID: sea-160167
ABSTRACT
The analgesic, dipyrone (l,phenyl 2,3 dimethyl 5 pyrazolone 4 methyl amino methane sulphonate sodium), at 20 mM concentration, inhibited the rejoining of single strand scissions in DNA of Escherichia coli B/r cells induced by 20 krad gamma radiation. The chemical altered the cell membrane structure as evidenced from the uptake of acriflavin, the efflux of potassium ions from the bacterial cells and the inhibition of alkaline phosphatase a cell membrane associated enzyme.
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Índice:
IMSEAR (Asia Sudoriental)
Idioma:
Inglés
Revista:
J Biosci
Año:
1982
Tipo del documento:
Artículo
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