Characterization of a toxin from Parthenium hysterophorus and its mode of excretion in animals.
J Biosci
;
1984 Dec; 6(5): 729-738
Artículo
en Inglés
| IMSEAR
| ID: sea-160410
ABSTRACT
Fractionation of methanolic extracts of air dried aerial parts of Parthenium resulted in the isolation of a toxic constituent which was identified as parthenin, the major sesquiterpene lactone from the weed. The LD50 (minimal lethal dose required to cause 50% mortality) for parthenin in rats was 42 mg/kg body weight. When [3H]-parthenin was given orally or by intravenous administration, radioactivity appeared in the milk of lactating laboratory and dairy animals. Tissue distribution of radioactivity revealed that maximum label was detectable in kidneys.
Texto completo:
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Índice:
IMSEAR (Asia Sudoriental)
Idioma:
Inglés
Revista:
J Biosci
Año:
1984
Tipo del documento:
Artículo
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