Europium (II) triflate catalyzed ring opening of oxiranes: an improved method for the synthesis of Β-amino alcohols.

ABSTRACT

Epoxides undergo rapidly ring-opening reaction with various amine nucleophiles in the presence of Europium triflate. The catalyst was very active and used in 10% mole only. All the reactions were carried out at room temperature in methylene dichloride to afford the corresponding b-amino alcohols in very good yields.