Propensity-matched analysis of association between preoperative anemia and in-hospital mortality in cardiac surgical patients undergoing valvular heart surgeries.
Ann Card Anaesth
;
2015 Jul; 18(3): 373-379
Artículo
en Inglés
| IMSEAR
| ID: sea-162338
ABSTRACT
Introduction:
Anaemia is associated with increased post-operative morbidity and mortality. We retrospectively assess the relationship between preoperative anaemia and in-hospital mortality in valvular cardiac surgical population. Materials andMethods:
Data from consecutive adult patients who underwent valvular repair/ replacement at our institute from January 2010 to April 2014 were collected from hospital records. Anaemia was defined according to WHO criteria (hemoglobin <13g/dl for males and <12g/dl for females). 11 matching was done for anemic and non-anemic patients based on propensity for potentially confounding variables. Logistic regression was used to evaluate the relationship between anaemia and in-hospital mortality. MatchIt package for R software was used for propensity matching and SPSS 16.0.0 was used for statistical analysis.Results:
2449 patients undergoing valvular surgery with or without coronary artery grafting were included. Anaemia was present in 37.1% (33.91% among males & 40.88% among females). Unadjusted OR for mortality was 1.6 in anemic group (95% Confidence Interval [95% CI] – 1.041-2.570; p=0.033). 11 matching was done on the basis of propensity score for anaemia (866 pairs). Balancing was confirmed using standardized differences. Anaemia had an OR of 1.8 for mortality (95% CI- 1.042 to 3.094, P=0.035). Hematocrit of < 20 on bypass was associated with higher mortality.Conclusion:
Preoperative anaemia is an independent risk factor associated with in-hospital mortality in patients undergoing valvular heart surgery.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Anciano
/
Femenino
/
Humanos
/
Masculino
/
Análisis de Supervivencia
/
Mortalidad Hospitalaria
/
Adulto
/
Cuidados Críticos
/
Periodo Preoperatorio
/
Procedimientos Quirúrgicos Cardíacos
Tipo de estudio:
Factores de riesgo
Idioma:
Inglés
Revista:
Ann Card Anaesth
Año:
2015
Tipo del documento:
Artículo
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