Development and histogenesis of human foetal lung in relation with gestational age.

ABSTRACT

Background: The objective was to study the development and histogenesis of human foetal lung in relation with different gestational age. Methods: In the present study lung specimens were collected from formalin fixed 27 aborted foetuses (14 male, 13 female) by abdominal dissection between 6 weeks to 40 weeks of gestational age. Results: In the present study we observed that there was a delay in the appearance of embryonic, pseudo glandular phase, canalicular, terminal saccular and alveolar stages of the lung. Conclusion: Delay in the developmental anatomy and histogenesis of the lung cells leads to histopathological abnormalities which gives knowledge to the clinicians during clinical procedures.