A Comparative Study of Antioxidant Levels in Farmers (Smokers and Nonsmokers) Exposed to Monocrotophos.

ABSTRACT

Despite extensive research in understanding toxic effects of monocrotophos, some uncertainty exists. The results showed a decrease in SOD activity both in smoker and non-smoker exposed groups when compared to the control group in the present study. The mean SOD activity in non-smoker control group was 1263±7.22 and the same has decreased to 496.0±9.123 in the non-smoker exposed group. Similarly a decrease in SOD activity was observed in smoker exposed group. While SOD activity in control group is 1258.3±12.79 it has decreased to 496.0±9.12 in the smokers exposed to monocrotophos pesticide. The results showed a decrease in GPX activity both in smoker and nonsmoker exposed groups when compared to the control group. The mean GPX activity in non-smoker control group was 20.62±4.14 and the same has decreased to10.75 ±2.87 in the non-smoker exposed group.