A Green Protocol for the Synthesis and Antimicrobial Evaluation of Some Imidazo [1,2-A] Pyrazines.

ABSTRACT

In this work, we have described a simple and convenient method for the synthesis Imidazo [1,2-a] pyrazine derivatives using 2-amino5-bromo pyrazine, and phenacyl bromide in the presence of DABCO as a catalyst and evaluated as antimicrobial agents. The notable features of this protocol are the simple experimental procedure, short reaction time, easy handling and good yields using a catalytic amount of readily available and cost effective catalyst.