The Analgesic and Adverse Effects of Intrathecal Opioids for Cesarean Section: 11 Years’ Experience in 10,061 Cases.

ABSTRACT

Purposes: To evaluate analgesic effect and adverse effects of intrathecal morphine and fentanyl in parturients undergoing cesarean section. Methods: This is a retrospective, descriptive study from anesthetic and recovery room records from January 2001 to August 2011. Results: From this 11-year retrospective, descriptive analysis in 10,061 patients undergoing cesarean section who received intrathecal opioids, it had been found that their pain scores both at rest and with movement were mild and moderate, respectively. Nausea / vomiting and pruritus were common complications but no patient experienced respiratory depression. Conclusions: Intrathecal morphine is effective for controlling postcesarean pain with minor adverse effects.