GC-MS Analysis and Antibacterial Activity of the Essential Oil Isolated from Wild Artemisia herba-alba Grown in South Jorda.
Br J Med Med Res
;
2015; 5(3): 297-302
Artículo
en Inglés
| IMSEAR
| ID: sea-175863
ABSTRACT
Background:
There is a high variability in chemical composition of essential oil from Artemisia herba-alba grown in different countries and different localities in the same country. This has led to the characterization of many oil-dependent chemotypes assigned to the plant. Only one report was published on the essential oil composition of Artemisia herba-alba grown in Jordan.Aim:
The current study aims to determines the essential oil composition of Artemisia herba-alba grown wild in south Jordan and test their activity against clinical isolate antibiotics resistant bacteria.Methodology:
The essential oils were isolated by hydrodistillation and analysed by Gas Chromatography-Mass Spectrometry (GC-MS). The screening for essential oil activity was carried out using disc diffusion method on methicillin-resistant Staphylococcus aureus, methicillin-sensitive Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumonia, Proteus mirabilis and Pseudomonas aeruginosa.Results:
Fifty-eight components accounting for 98.8% of the oil were identified, with oxygenated monoterpenes accounting for about 75% of the total oil content. Major identified compounds were cis-chrysanthenol (13.83%), 1,8-cineole (12.84%), cis-limonene (12.57%), α-terpinenol (6.97%), and γ-muurolene (4.50%). The volatile fractions exhibited potent activity against all resistant strains except Pseudomonas aeruginosa.Conclusion:
We report here a new chemotype of Artemisia herba-alba grown in Jordan characterized by the presence of chrysanthenol, 1, 8-cineole, cis-limonene, and α-terpinenol.
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IMSEAR (Asia Sudoriental)
Idioma:
Inglés
Revista:
Br J Med Med Res
Año:
2015
Tipo del documento:
Artículo
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