A rare case of multicentric secretory carcinoma of breast in an adult female with review of literature.
Indian J Pathol Microbiol
;
2016 Apr-June 59(2): 209-211
Artículo
en Inglés
| IMSEAR
| ID: sea-179479
ABSTRACT
Secretory breast carcinomas (SBCs) are considered one of the rarest types of BCs accounting for <0.15% of all breast cancers. The lesions are typically solitary, but rare multicentric cases have been reported. SBC have characteristic histopathological, immunohistochemical, and electron microscopic findings. Children and adolescents with SBC have a favorable prognosis, but disease seems slightly more aggressive in adults. The characteristic ETV6‑NTRK3 molecular alteration, leading to a stable chimeric tyrosine kinase fusion product, may be the target of promising new treatment for this unique BC. We present a rare case of multicentric secretory carcinoma of breast with aggressive clinical behavior in a 75‑year‑old female.
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IMSEAR (Asia Sudoriental)
Tipo de estudio:
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian J Pathol Microbiol
Año:
2016
Tipo del documento:
Artículo
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