Your browser doesn't support javascript.
loading
Efficacy and Tolerability of Trandolapril in Mildto- moderate Hypertension: A Double-blind Comparison with Enalapril.
Artículo en Inglés | IMSEAR | ID: sea-182308
ABSTRACT

Objective:

To compare the efficacy and tolerability between trandolapril and enalapril in mild-to-moderate hypertension. Material and

Methods:

This was a prospective, double-blind, parallel, comparative clinical trial involving 120 patients with mild-to-moderate hypertension. Patients were randomized to receive trandolapril 2-4 mg once-daily and enalapril 5-10 mg once-daily. The participants were followed for eight weeks.

Results:

Both the drugs achieved effective control of blood pressure (BP) at the end of eight weeks. The mean reduction in systolic BP (SBP) was 22.17 mmHg with trandolapril and 21.47 mmHg with enalapril group; the mean reduction of diastolic BP (DBP) was 9.57 mmHg with trandolapril and 11.13 mmHg with enalapril. Adverse events developed in 11 (18.3%) and 12 (20%) patients in trandolapril and enalapril group, respectively.

Conclusion:

The efficacy and tolerability of trandolapril was comparable to enalapril in mild-to-moderate hypertension with minor adverse events.

Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Tipo de estudio: Ensayo Clínico Controlado Idioma: Inglés Año: 2012 Tipo del documento: Artículo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Tipo de estudio: Ensayo Clínico Controlado Idioma: Inglés Año: 2012 Tipo del documento: Artículo