Effect of nepafenac 0.1% on macular thickness during immediate post operative period after phacoemulsification in patients with low risk for cystoid macular edema.

ABSTRACT

Introduction: To evaluate the effect of nepafenac 0.1% after routine phacoemulsification in patient at low risk for cystoids macular edema. Material and methods: This prospective hospital based study consists of 70 eyes of 70 subject with no risk factor for cystoid macular edema who underwent phacoemulsification by an experienced surgeon. All 70 subjects received preoperative nepafenac. 35 subjects received nepafenac post operatively (treatment). SD OCT (Spectral domain optical coherence tomography) and visual acuity measurement were taken pre op and post op (1 week, 1month). Final end point where comparison of macular thickness and visual acuity between two group. Result: All subjects in this study had excellent visual outcome post cataract extraction. There was small increase in macular thickness in both treatment and control group with no difference in visual acuity between first and second post op visits. Conclusion: There is an increase in macular thickness measured by OCT in low risk patients after phacoemulsification there was no clinical effect on final visual acuity.