Simulation Analysis for Non-invasive Measurement for Hemodynamics in Cerebral Arteriovenous Malformation Types.

ABSTRACT

The Cerebral Arteriovenous Malformation (CAVM) is a complex neurovascular malformation. It contains different types of complex nidus structures combinations. Each CAVM classification is of different clinical procedure and management of disease. The clinical procedure to measure hemodynamics for each CAVM classification is risky, due to complex vessel geometry may get ruptured. In this paper, we address this problem for different AVM classification and nidus complex structures combinations, by measuring hemodynamics non-invasively. The simulation of model is extended for organs other than Cerebral AVM, such as spine and lungs. The modeling results are validated with mechanical measurements. 15 CAVM patients and 20 simulated scenarios of different AVM types are studied to measure hemodynamic indices non-invasively.