Fluoroquinolones At The Back Foot : A Study On Fluoroquinolone Resistance In Enterococcus Species Isolated From Urinary Specimens In A Tertiary Care Hospital In Kolkata, India

ABSTRACT

OBJECTIVE: The study aims to detect the resistance pattern of fluoroquinolones (ciprofloxacin & levofloxacin) in Urinary Tract Infection (UTI) caused by Enterococcus species. MATERIALS AND METHOD: 77 isolates of Enterococcus species from the urine samples of clinically suspected cases of UTI were studied. Identification and antimicrobial susceptibility testing was performed by conventional as well as automated methods. RESULT: Enterococcus faecalis (53.25%) was the commonest. Most of the isolates were resistant to both levofloxacin (83.12%) and ciprofloxacin (85.71%). • CONCLUSION: Resistance to fluoroquinolones is of concern as it serves as an excellent oral choice of drug. So, the inclusion of this group of drug in the treatment regime should be reconsidered and effective strategies developed to contain the same.