Holt-Oram Syndrome Rare Hand-Heart Disorder

ABSTRACT

Back ground Holt-Oram is rare autosomal disorder, clinically characterised by congenital cardiac defects and morphological abnormalities of the upper limbs. Case characteristics10 days old neonate born to first degree consangunious parents presented with upper limb anomaly and cardiac defects. Obseravations Hypoplastic left thumb with ASD, VSD and PDAwas present. Message- Neonate with upper limb anomaly should be evaluated for congenital hear disease