Genetic Syndromes Associated with Cleft Lip and Palate – A Review

ABSTRACT

Several syndromes are associated with cleft lip and cleft palate. Apart from the several syndromes reported in cleft lip and palate, syndromes require special attention, which are certain Velocardiofacial syndrome, Van der Woude syndrome (VWS), Stickler syndrome. Van der Woude, Foetal alcohol syndrome, Holzgreve syndrome, Marfan syndrome, Myotonic dystrophy, Klippel–Feil syndrome, Patau syndrome, Potter sequence and Pierre Robin sequence are also some of the syndromes which have been associated with cleft lip and palate. Certain measures such as multidisciplinary approach and family counselling may prove to be beneficial to treat cleft lip and palate.