To study the changes in lipid profile induced after ingestion of single high-cholesterol test meal in subjects of chronic liver disease and chronic renal disease

ABSTRACT

Chronic kidney disease (CKD), also known as chronic renal disease, is progressive loss in kidney function over a period of months or years. The symptoms of worsening kidney function are not specific, and might include feeling generally unwell and experiencing a reduced appetite. Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis. "Chronic liver disease" refers to disease of the liver which lasts over a period of six months. It consists of a wide range of liver pathologies which include inflammation (chronic hepatitis), liver cirrhosis, and hepatocellular carcinoma. The entire spectrum need not be experienced. Lipid profile or lipid panel is a panel of blood tests that serves as an initial broad medical screening tool for abnormalities in lipids, such as cholesterol and triglycerides. The results of this test can identify certain genetic diseases and can determine approximate risks for cardiovascular disease, certain forms of pancreatitis, and other diseases. Aim of the present study To study the changes in Lipid Profile M. Madan Mohan Rao, Shivnath Nandan, G. Obulesu, Salma Mahaboob R. To study the changes in lipid profile induced after ingestion of single high-cholesterol test meal in subjects of chronic liver disease and chronic renal disease. IAIM, 2017; 4(1) 50-57. Page 51 Induced after Ingestion of Single High-Cholesterol Test Meal in Subjects of Chronic Liver Disease and Chronic Renal Disease. Materials and methods, present study was conducted in the department of General Medicine, RIMS, Kadapa, by taking 50 patients of both the sexes. Serum was separated within four hours by centrifugation and the tests are serum total cholesterol (STC), serum Triglycerides (STG), HDL-cholesterol, LDL-cholesterol and VLDL-Cholesterol. Statistical analysis of the data was done by using paired ‘t’ test and student ‘t’ test. As no such comparative prior studies have been done on COPD patients, it was strongly urged that further studies with larger sample groups be carried out to elucidate the quantitative and qualitative significance of these changes.