Incidence of malignancy in intestinal polyp of Peutz-Jeghers Syndrome: Case Series
Artículo
| IMSEAR
| ID: sea-187342
ABSTRACT
Introduction:
Peutz-Jeghers syndrome is also known as “Hereditary Intestinal Polyposis Syndrome”. It is an autosomal dominant disease, characterized by the development of benign hamartomatous and adenomatous polyps in the gastrointestinal tract, and hyperpigmented macules on the lips, nostrils, buccal mucosa, palmer surfaces of the hands, genitalia and perianal region. Its incidence is 1 in 200000 births. 25 cases of Peutz-Jeghers Syndrome were studied in tertiary health centre. Diagnosis of Peutz-Jeghers Syndrome was made on the basis of clinical details, radiology reports and the histopathological study. The patients were from both urban and rural areas of Ujjain. The entire study was retrospective study. Aims andObjectives:
To study the incidence of malignancy in intestinal polyp of Peutz-Jeghers Syndrome. Materials andMethods:
Polyps from patients with Peutz-Jeghers Syndrome were studied in the histopathology department. The corresponding medical records were reviewed to confirm that the diagnosis of Peutz-Jeghers Syndrome. Hematoxylin and Eosin (H&E) stain was used for the histopathological diagnosis. Particular attention was paid to the presence and pattern of distribution of network of connective tissue, smooth muscle, lamina propria and glands lined by intestinal epithelium. Results andConclusion:
We evaluated colonic polyps from 25 patients of Peutz-Jeghers Syndrome. Out of all patients, none of the intestinal polyps turned out to be malignant. The incidence of malignancy in intestinal polyps in Peutz-Jeghers Syndrome as per this study is insignificant.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Tipo de estudio:
Estudio de incidencia
/
Estudio observacional
Año:
2019
Tipo del documento:
Artículo
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