A Comparative Study of Lipid Profile in Type I and Type II Diabetes

ABSTRACT

Background:Prevalence of D.M. has been steadily increasing in urban as well as rural areas in India & it will be one of the major cause of death in India in 21st century. Pattern of dyslipidemia is found to be different in Type I & Type II diabetes mellitus (DM). Aims and objectives: 1) Estimation of lipid profile in Type I and Type II DM. 2) Comparison of Lipid Profile in Type I and Type II DM. Material and methods: 50 patients of each already diagnosed Type I and Type II DM patients visiting OPD. 50 age and sex matched healthy controls. FPG (Fasting Plasma Glucose) and lipid profile were studied in the groups. Statistics Students‘t’ test was used. Results: FPG and TC, TG, LDL-C, VLDL-C were significantly high in both Type I and Type II DM compared to the controls. While HDL-C was significantly lower in diabetics compared to the controls. Among the diabetics all the parameters were significantly high in Type IIDM compared to Type I DM exceot HDL-C in which no significant difference was found. Conclusion: Glycaemic control is poorer in Type II DM compared to Type I DM. Also, dyslipidaemia is more prominent in Type II DM than in Type I DM.