Study of Adverse Donor Reaction of Plateletpheresis in a Tertiary Care Centre of North India

ABSTRACT

Background: Plateletpheresis is a lifesaving procedure in preventing and treating serious complications from bleeding and haemorrhage in patients having disorders manifesting as thrombocytopenia like in dengue patients, ITP, aplastic anemia and chemotherapy for leukaemia. Methods: In this study 100 healthy voluntary donors were enrolled after taking the informed written consent and adverse donor reactions of plateletpheresis were noted. Results: It was observed that out of 100 donors, only two donors had adverse effects during plateletphersis. Citrate toxicity was seen in one donor (1%) and one donor (1%) had bruising on the arm at venipuncture site during phlebotomy. Conclusion: Plateletphersis is one of the safest procedure in which adverse effects were managed conservatively and rarely donor need hospitalisation.